Stem Cell Therapy - The future of dentistry | AIMS Dentistry




For ages man have desired renewal of permanent teeth. How wonderful it could have been if we could have an infinite set of teeth like sharks.

Stem cell therapy is a step forward in that direction. When implemented successfully, it'll open new avenues not just in the world of dentistry but in other areas like connective tissue disorders, Alzheimer's, cancer treatment, bone fractures etc.

The application of stem cell therapy is universal. But what is it all about?
Stem cells are the primitive cells that have the capacity to multiply and differentiate into any mature cell. There has been a wide spread awareness regarding cryogenically preserving the umbilical cord for its stem cells for future use.

Stem cells are of two types: embryonic and adult stem cells.
Adult stem cells can be harvested from bone marrow, placenta, synovial membrane, adipose tissue, liver, and even teeth. These cells have the capability to multiply and differentiate into specialized cells such as blood cells, cartilage, bone, etc.

Similarly, periodontal ligament stem cells can be used in periodontal regeneration. These cells exhibit a higher rate of proliferation as compared to cultured bone marrow stromal stem cells.

Clinical application of stem cell therapy

Mesenchymal stem cells have the potential to regenerate mammalian dental tissue that will be a huge breakthrough in the future. Cultured dental pulp stem cells can be developed into bioengineered teeth, having well developed pulp chambers, odontoblasts, predentin, dentin, and even morphologically correct enamel organ. It has been demonstrated that dental pulp stem cells are capable of generating a reparative dentin like structure directly on the surface of human dentin.

In gene-enhanced periodontal regeneration, the regenerative property of periodontal ligament stem cells is regained to initiate the formation of both dental and periodontal attachment tissues. It's simply mimicking the natural process that occurs during development.

On success, it'll be a whole new experience. Teeth will regain the power to repair themselves and tooth extractions can be followed by growth of new dental tissue. Even though this technology will take considerable time to develop, it's certainly not a distant futuristic dream.

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